Publications

2025

1. Deveney, B.T.; Heyman, J.A.; Rosenthal, R.G.; Weitz, D.A.; Werner, J.G. A biocompatible surfactant film for stable microfluidic droplets. Lab on a Chip 2025.  A biocompatible surfactant film for stable microfluidic dropletsPublisher's Version A biocompatible surfactant film for stable microfluidic dropletsPDF
2. Yang, C.; Menge, J.; Zhvania, N.; Yu, M.; Yang, H.; Chen, D.; Zheng, Z.; Weitz, D.A.; Jahnke, K. Engineering Asymmetric Nanoscale Vesicles for mRNA and Protein Delivery to Cells. Advanced Functional Materials 2025, 35, 2505738.  Engineering Asymmetric Nanoscale Vesicles for mRNA and Protein Delivery to CellsPublisher's Version Engineering Asymmetric Nanoscale Vesicles for mRNA and Protein Delivery to CellsPDF
3. Wang, X.; Li, W.; Lou, W.; Li, W.; Zhang, L.; Weitz, D.A. Single-Cell Microgel Microrobot for Targeted and Imaging-Guided Cell Therapy. CCS Chemistry 2025.  Single-Cell Microgel Microrobot for Targeted and Imaging-Guided Cell TherapyPublisher's Version Single-Cell Microgel Microrobot for Targeted and Imaging-Guided Cell TherapyPDF
4. Thorne, B.; Xu, J.; Mahavadi, S.C.; Song, Y.-S.; Weitz, D.A. Contact Angle Mapping Using Microdroplets. Langmuir 2025, 41, 21869–21877.  Contact Angle Mapping Using MicrodropletsPublisher's Version Contact Angle Mapping Using MicrodropletsPDF
5. Guo, M.; Wong, I.Y.; Moore, A.S.; Medalia, O.; Lippincott-Schwartz; Weitz, D.A.; Goldman, R.D. Vimentin intermediate filaments as structural and mechanical coordinators of mesenchymal cells. Nat Cell Biol 2025, 27, 1210–1218.  Vimentin intermediate filaments as structural and mechanical coordinators of mesenchymal cellsPublisher's Version Vimentin intermediate filaments as structural and mechanical coordinators of mesenchymal cellsPDF
6. Chen, A.; Xu, W.; Zhang, X.D.; Lao, J.; Zhao, X.; Milcic, K.; Weitz, D.A. Ultrahigh-Throughput Multiplexed Screening of Purified Protein from Cell-Free Expression Using Droplet Microfluidics. J. Am. Chem. Soc. 2025, 147, 28758–28772.  Ultrahigh-Throughput Multiplexed Screening of Purified Protein from Cell-Free Expression Using Droplet MicrofluidicsPublisher's Version Ultrahigh-Throughput Multiplexed Screening of Purified Protein from Cell-Free Expression Using Droplet MicrofluidicsPDF
7. Yang, G.; Liu, Y.; Devkota, S.R.; Hui, Y.; Zhao, R.; Li, Y.; Weitz, D.A.; Zhao, C.-X. A Sustainable Biotechnology Approach for Mineral Separation. Advanced Functional Materials 2025, e04992.  A Sustainable Biotechnology Approach for Mineral SeparationPublisher's Version A Sustainable Biotechnology Approach for Mineral SeparationPDF
8. Ren, L.; Shi, J.; Liu, S.; Wang, Z.; Qiao, S.; Weitz, D.A.; Zhang, L. Tough Hybrid Hydrogels with Exceptional Swollen-State Mechanical Robustness via Nanocrystalline Domain Engineering. Macromolecules 2025, 58, 7975–7985.  Tough Hybrid Hydrogels with Exceptional Swollen-State Mechanical Robustness via Nanocrystalline Domain EngineeringPublisher's Version Tough Hybrid Hydrogels with Exceptional Swollen-State Mechanical Robustness via Nanocrystalline Domain EngineeringPDF
9. Wilborn, A.M.; Almohammadi, H.; Qu, P.; Wang, Y.; Yang, Y.; Kay, R.; Kim, D; Bertoldi, K.; Weitz, D.A.; Aizenberg, J. Towards Differentiation in Untethered Microactuators: A Soft Fabrication Strategy. Advanced Materials 2025, 2507273.  Towards Differentiation in Untethered Microactuators: A Soft Fabrication StrategyPublisher's Version Towards Differentiation in Untethered Microactuators: A Soft Fabrication StrategyPDF
10. Zhang, J.; Liu, R.; Yang, Z.; Luo, C.; Chen, J.; Guo, B.; Weitz, D.A.; Chen, D. Physicochemical and Surface Properties of Nanoparticles: Effects on Cellular Pathway and Uptake. ChemNanoMat 2025, 11, e202500043.  Physicochemical and Surface Properties of Nanoparticles: Effects on Cellular Pathway and UptakePublisher's Version Physicochemical and Surface Properties of Nanoparticles: Effects on Cellular Pathway and UptakePDF

1. Liu, C.; Liu, Y.; Xue, C.; Yang, C.; Weitz, D.A.; Jahnke, K. Engineering Liposomes with Cell Membrane Proteins to Disrupt Melanosome Transfer between Cells. ACS Nano 2025, 19, 22988–23000.  Engineering Liposomes with Cell Membrane Proteins to Disrupt Melanosome Transfer between CellsPublisher's Version Engineering Liposomes with Cell Membrane Proteins to Disrupt Melanosome Transfer between CellsPDF
2. Wu, Z.; Werner, J.G.; Weitz, D.A. Dynamic Poly(amine) Capsules with Reversible pH-Triggered Responsiveness. ACS Appl. Polym. Mater. 2025, 7, 7893–7898.  Dynamic Poly(amine) Capsules with Reversible pH-Triggered ResponsivenessPublisher's Version Dynamic Poly(amine) Capsules with Reversible pH-Triggered ResponsivenessPDF
3. Terdik, J.Z.; Weitz, D.A.; Spaepen, F. Fabrication and mounting of near-critical silicone gels for mechanical testing of colloidal solids. Rev. Sci. Instrum. 2025, 96, 053902.  Fabrication and mounting of near-critical silicone gels for mechanical testing of colloidal solidsPublisher's Version Fabrication and mounting of near-critical silicone gels for mechanical testing of colloidal solidsPDF
4. Erkamp, N.A.; Farag, M.; Qiu, Y.; Qian, D.; Sneideris, T.; Wu, T.; Welsh, T.J.; Ausserwoger, H.; Krug, T.J.; Chauhan, G.; Weitz, D.A.; Lew, M.D.; Knowles, T.P.J.; Pappu, R.V. Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates. Nature Communications 2025, 16, 3463.  Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensatesPublisher's Version Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensatesPDF
5. Shen, W.; Chen, A.; Paink, G.K.; Black, N.; Weitz, D.A.; Mazur, E. Cargo Delivery to Cells Using Laser-Irradiated Carbon-Black-Loaded Polydimethylsiloxane. ACS Materials Lett. 2025, 7, 1754–1759.  Cargo Delivery to Cells Using Laser-Irradiated Carbon-Black-Loaded PolydimethylsiloxanePublisher's Version Cargo Delivery to Cells Using Laser-Irradiated Carbon-Black-Loaded PolydimethylsiloxanePDF
6. Basu, A.; Krug, T.; du Pont, B.; Huang, Q.; Sun, S.; Adam, S.A.; Goldman, R.D.; Weitz, D.A. Vimentin undergoes liquid–liquid phase separation to form droplets which wet and stabilize actin fibers. PNAS 2025, 122, e2418624122.  Vimentin undergoes liquid–liquid phase separation to form droplets which wet and stabilize actin fibersPublisher's Version Vimentin undergoes liquid–liquid phase separation to form droplets which wet and stabilize actin fibersPDF
7. Meyer, C.; Chen, A.; Weitz, D.A.; Mooney, D.J. Immobilization of BMP-2 in porous hydrogels to spatially regulate osteogenesis. Journal of Controlled Release 2025, 379, 944-950.  Immobilization of BMP-2 in porous hydrogels to spatially regulate osteogenesisPublisher's Version Immobilization of BMP-2 in porous hydrogels to spatially regulate osteogenesisPDF
8. Wang, Z.; Xia, J.; Garry, R.; Weitz, D.A.; Li, X. Recent progress on acoustofluidic manipulation of cells and particles. NSO 2025, 4, 20230080.  Recent progress on acoustofluidic manipulation of cells and particlesPublisher's Version Recent progress on acoustofluidic manipulation of cells and particlesPDF
9. Litschel, T.; Vavylonis, D.; Weitz, D.A. BPS2025 – 3D-Printing cytoskeletal networks: Reactive oxygen species induce a surge in actin polymerization. Biophysical Journal 2025, 124, 376A.  BPS2025 - 3D-Printing cytoskeletal networks: Reactive oxygen species induce a surge in actin polymerizationPublisher's Version BPS2025 - 3D-Printing cytoskeletal networks: Reactive oxygen species induce a surge in actin polymerizationPDF
10. Jahnke, K.; Yang, C.; Weitz, D.A. Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densities. Biophysical Journal 2025, 124, 91A.  Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densitiesPublisher's Version Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densitiesPDF
11. Xu, Z.; Zhu, C.; Shen, H.; Liu, Y; Tang, J.; Weitz, D.A.; Xu, L. Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densities. PNAS 2025, 122, e2423426122.  Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densitiesPublisher's Version Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densitiesPDF
12. Wu, Z.; Deveney, B.T.; Werner, J.G.; Aime, S.; Weitz, D.A. Fluorophilic boronic acid copolymer surfactant for stabilization of complex emulsion droplets with fluorinated oil. Lab on a Chip 2025, 25, 2315-2319.  Fluorophilic boronic acid copolymer surfactant for stabilization of complex emulsion droplets with fluorinated oilPublisher's Version Fluorophilic boronic acid copolymer surfactant for stabilization of complex emulsion droplets with fluorinated oilPDF
13. Salomon, R.; Bazaz, S.R.; Mutafopulos, K.; Gallego-Ortega, D.; Warkiani, M.; Weitz, D.A.; Jin, D. Challenges in blood fractionation for cancer liquid biopsy: how can microfluidics assist?. Lab on a Chip 2025, 25, 1097-1127.  Challenges in blood fractionation for cancer liquid biopsy: how can microfluidics assist?Publisher's Version Challenges in blood fractionation for cancer liquid biopsy: how can microfluidics assist?PDF
14. Xie, Y.; Yang, Z.; Shen, H.; Chen, J.; Weitz, D.A.; Chen, D.; Sheng, J.; Liang, T. Interfacial Engineering of Biocompatible Nanocapsules for Near-Infrared-Triggered Drug Release and Photothermal Therapy. Advanced Science 2025, 12, 2410844.  Interfacial Engineering of Biocompatible Nanocapsules for Near-Infrared-Triggered Drug Release and Photothermal Therapy Publisher's Version  Interfacial Engineering of Biocompatible Nanocapsules for Near-Infrared-Triggered Drug Release and Photothermal Therapy PDF
15. Xie, Y.; Yang, Z.; Shen, H.; Chen, J.; Weitz, D.A.; Chen, D.; Sheng, J.; Liang, T. Interfacial Engineering of Biocompatible Nanocapsules for Near-Infrared-Triggered Drug Release and Photothermal Therapy. Advanced Science 2025, 12, 2410844.  Interfacial Engineering of Biocompatible Nanocapsules for Near-Infrared-Triggered Drug Release and Photothermal Therapy Publisher's Version  Interfacial Engineering of Biocompatible Nanocapsules for Near-Infrared-Triggered Drug Release and Photothermal Therapy PDF
16. Pu, X. ; Liu, R. ; Xie, Y. ; Yang, C. ; Chen, J. ; Guo, B. ; Chao, C. – X. ; Zhao, P. ; Ruan, J. ; Ye, F. ; Weitz, D.A.; Chen, D. One-step preparation of biocompatible amphiphilic dimer nanoparticles with tunable particle morphology and surface property for interface stabilization and drug delivery. Chinese Chemical Letters 2025, 36, 109820.  One-step preparation of biocompatible amphiphilic dimer nanoparticles with tunable particle morphology and surface property for interface stabilization and drug deliveryPublisher's Version