Publications by Year: 2017

Ung, W. L. ; Mutafopulos, K. ; Spink, P. ; Rambach, R. W. ; Franke, T. ; Weitz, D. A. Enhanced Surface Acoustic Wave Cell Sorting by 3D Microfluidic-Chip Design. Lab on a Chip 2017, 17, 4059-4069. Publisher's VersionAbstract
We demonstrate an acoustic wave driven microfluidic cell sorter that combines advantages of multilayer device fabrication with planar surface acoustic wave excitation. We harness the strong vertical component of the refracted acoustic wave to enhance cell actuation by using an asymmetric flow field to increase cell deflection. Precise control of the 3-dimensional flow is realized by topographical structures implemented on the top of the microchannel. We experimentally quantify the effect of the structure dimensions and acoustic parameter. The design attains cell sorting rates and purities approaching those of state of the art fluorescence-activated cell sorters with all the advantages of microfluidic cell sorting.
Chaudhuri, M. ; Allahyarov, E. ; Löwen, H. ; Egelhaaf, S. U. ; Weitz, D. A. Triple Junction at the Triple Point Resolved on the Individual Particle Level. Phys. Rev. Lett. 2017, 119, 128001. 2017_prl_chaudhrui.pdf
Zhao, C. - X. ; Chen, D. ; Hui, Y. ; Weitz, D. A. ; Middelberg, A. P. J. Controlled Generation of Ultrathin-Shell Double Emulsions and Studies on Their Stability. ChemPhysChem 2017, 18, 1393–1399. 2017_chemphyschem_zhao_1.pdf
Beroz, F. ; Jawerth, L. M. ; Münster, S. ; Weitz, D. A. ; Broedersz, C. P. ; Wingreen, N. S. Physical limits to biomechanical sensing in disordered fibre networks. Nature communications 2017, 8 16096. 2017_natcomm_beroz.pdf
Kong, L. ; Amstad, E. ; Hai, M. ; Ke, X. ; Chen, D. ; Zhao, C. - X. ; Weitz, D. A. Biocompatible microcapsules with a water core templated from single emulsions. Chinese Chemical Letters 2017, 28, 1897-1900. Publisher's Version kong2017.pdf
Fan, J. ; Kim, S. - H. ; Chen, Z. ; Zhou, S. ; Amstad, E. ; Lin, T. ; Weitz, D. A. Creation of Faceted Polyhedral Microgels from Compressed Emulsions. Small 2017. 2017_small_fan.pdf
Zhang, W. ; Abbaspourrad, A. ; Chen, D. ; Campbell, E. ; Zhao, H. ; Li, Y. ; Li, Q. ; Weitz, D. A. Osmotic Pressure Triggered Rapid Release of Encapsulated Enzymes with Enhanced Activity. Advanced Functional Materials 2017. 2017_afm_zhang.pdf
Amstad, E. ; Chen, X. ; Eggersdorfer, M. ; Cohen, N. ; Kodger, T. E. ; Ren, C. L. ; Weitz, D. A. Parallelization of microfluidic flow-focusing devices. Physical Review E 2017, 95, 043105. 2017_pre_amstad.pdf
Kodger, T. E. ; Lu, P. J. ; Wiseman, G. R. ; Weitz, D. A. Stable, fluorescent PMMA particles for long-term observation of slow colloidal dynamics. Langmuir 2017. 2017_langmuir_kodger.pdf
Atia, L. ; Bi, D. ; Sharma, Y. ; Mitchel, J. A. ; Gweon, B. ; Koehler, S. ; DeCamp, S. J. ; Lan, B. ; Hirsch, R. ; Pegoraro, A. F. ; et al. Universal geometric constraints during epithelial jamming. arXiv preprint arXiv:1705.04660 2017. 2017_arxiv_atia.pdf
Haliburton, J. R. ; Kim, S. C. ; Clark, I. C. ; Sperling, R. A. ; Weitz, D. A. ; Abate, A. R. Efficient extraction of oil from droplet microfluidic emulsions. Biomicrofluidics 2017, 11, 034111. 2017_biomicrofluidics_abate.pdf
Prakadan, S. M. ; Shalek, A. K. ; Weitz, D. A. Scaling by shrinking: empowering single-cell'omics' with microfluidic devices. Nature Reviews Genetics 2017. 2017_natgenrev_prakadan.pdf
Qin, Y. ; Hu, Y. ; Koehler, S. A. ; Cai, L. ; Wen, J. ; Tan, X. ; Xu, W. L. ; Sheng, Q. ; Hou, X. ; Xue, J. ; et al. Ultrafast Nanofiltration through Large-Area Single-layered Graphene Membranes. ACS Applied Materials & Interfaces 2017. 2017_acsappmaterinfer_qin.pdf
He, Y. ; Battat, S. ; Fan, J. ; Abbaspourrad, A. ; Weitz, D. A. Preparation of microparticles through co-flowing of partially miscible liquids. Chemical Engineering Journal 2017, 320, 144-150. Publisher's Version he2017.pdf
Eggersdorfer, M. L. ; Koren, V. ; Stolovicki, E. ; Amstad, E. ; Weitz, D. A. Rapid Production of Submicron Drug Substance Particles by Supersonic Spray Drying. Crystal Growth & Design 2017. 2017_CGD_Eggersdorfer.pdf
Yissachar, N. ; Zhou, Y. ; Ung, L. ; Lai, N. Y. ; Mohan, J. F. ; Ehrlicher, A. ; Weitz, D. A. ; Kasper, D. L. ; Chiu, I. M. ; Mathis, D. ; et al. An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk. Cell 2017, 168, 1135–1148. 2017_cell_yissachar.pdf
Qu, X. ; Zhang, H. ; Chen, H. ; Aldalbahi, A. ; Li, L. ; Tian, Y. ; Weitz, D. A. ; Pei, H. Convection Driven Pull-Down Assays in Nanoliter Droplets using Scaffolded Aptamers. Analytical Chemistry 2017. 2017_anachem_qu.pdf
Sprakel, J. ; Zaccone, A. ; Spaepen, F. ; Schall, P. ; Weitz, D. A. Direct Observation of Entropic Stabilization of bcc Crystals Near Melting. Physical Review Letters 2017, 118, 088003. 2017_prl_sprakel.pdf
Amato, D. V. ; Lee, H. ; Werner, J. G. ; Weitz, D. A. ; Patton, D. L. Functional Microcapsules via Thiol- Ene Photopolymerization in Droplet-Based Microfluidics. ACS applied materials & interfaces 2017, 9 3288–3293. 2017_acsappmaterinfer_amato.pdf
Kalinich, M. ; Bhan, I. ; Kwan, T. T. ; Miyamoto, D. T. ; Javaid, S. ; LiCausi, J. A. ; Milner, J. D. ; Hong, X. ; Goyal, L. ; Sil, S. ; et al. An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma. Proceedings of the National Academy of Sciences 2017, 201617032. 2017_pnas_kalinich.pdf