Functionalized glass coating for PDMS microfluidic devices

Citation:

Abate, A. R. ; Lee, D. ; Holtze, C. ; Krummel, A. ; Do, T. ; Weitz, D. A. Functionalized glass coating for PDMS microfluidic devices. In Lab-on-a-Chip Technology (Vol. 1): Fabrication and Microfluidics; Caister Academic Press, 2009; Vol. 1. Copy at http://www.tinyurl.com/yz9wvuum

Abstract:

Microfluidic devices can perform multiple laboratory functions on a single, compact, and fully integrated chip. However, fabrication of microfluidic devices is difficult, and current methods, such as glass-etching or soft-lithography in PDMS, are either expensive or yield devices with poor chemical robustness. We introduce a simple method that combines the simple fabrication of PDMS with superior robustness and control of glass. We coat PDMS channels with a functionalized glass layer. The glass coating greatly increases the chemical robustness of the PDMS devices. As a demonstration, we produce emulsions in coated channels using organic solvents. The glass coating also enables surface properties to be spatially controlled. As a demonstration of this control, we spatially pattern the wettability of coated PDMS channels and use the devices to produce double emulsions with fluorocarbon oil.

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