@article {han2015whole,
	title = {Whole-Genome Sequencing of a Single Viral Species from a Highly Heterogeneous Sample},
	journal = {Angewandte Chemie},
	volume = {54},
	number = {47},
	year = {2015},
	pages = {13985-13988},
	publisher = {WILEY-VCH Verlag},
	abstract = {
	
		Metagenomic studies suggest that only a small fraction of the viruses that exist in nature have been identified and studied. Characterization of unknown viral genomes is hindered by the many genomes populating any virus sample. A new method is reported that integrates drop-based microfluidics and computational analysis to enable the purification of any single viral species from a complex mixed virus sample and the retrieval of complete genome sequences. By using this platform, the genome sequence of a 5243 bp dsDNA virus that was spiked into wastewater was retrieved with greater than 96 \% sequence coverage and more than 99.8 \% sequence identity. This method holds great potential for virus discovery since it allows enrichment and sequencing of previously undescribed viruses as well as known viruses.
	

},
	url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201507047},
	author = {Han, Hee-Sun and Cantalupo, Paul G. and Rotem, Assaf and Cockrell, Shelley K. and Carbonnaux, Martial and Pipas, James M. and Weitz, David A}
}
