@article {eggersdorfer2017tandem, title = {Tandem emulsification for high-throughput production of double emulsions}, journal = {Lab on a Chip}, volume = {17}, number = {5}, year = {2017}, pages = {936{\textendash}942}, publisher = {Royal Society of Chemistry}, abstract = { Core{\textendash}shell double emulsions produced using microfluidic methods with controlled structural parameters exhibit great potential in a wide range of applications, but the low production rate of microfluidic methods hinders the exploitation of the capabilities of microfluidics to produce double emulsions with well-defined features. A major obstacle towards the scaled-up production of core{\textendash}shell double emulsions is the difficulty of achieving robust spatially controlled wettability in integrated microfluidic devices. Here, we use tandem emulsification, a two-step process with microfluidic devices, to scale up the production. With this method, single emulsions are generated in a first device and are re-injected directly into a second device to form uniform double emulsions. We demonstrate the application of tandem emulsification for scalable core{\textendash}shell emulsion production with both integrated flow focusing and millipede devices and obtain emulsions of which over 90\% are single-core monodisperse double emulsion drops. With both mechanisms, the shell thickness can be controlled, so that shells as thin as 3 μm are obtained for emulsions 50 μm in radius. }, url = {https://pubs.rsc.org/en/content/articlelanding/2017/lc/c6lc01553k$\#$!divAbstract}, author = {Eggersdorfer, ML and Zheng, W. and S. Nawar and Mercandetti, C and Ofner, A and Leibacher, I and Koehler, S and Weitz, D. A.} }