Drug dissolution chip (DDC): A microfluidic approach for drug release

windbergs2011.pdf749 KB

Abstract:

The first pharmaceutical dissolution testing device for multiparticulate drug delivery systems on a microfluidic chip is presented. This versatile platform technology allows for simultaneous analysis of the drug concentration in the dissolution medium and of the solid parts of the sample immobilized in the device with different analytical techniques. By mimicking the fate of drug release in the human body, this can contribute to the optimization of therapeutic effectiveness during the development of novel drug release systems.

Publisher's Version

Last updated on 03/31/2021