Designer emulsions using microfluidics


Shah, R. K. ; Shum, H. C. ; Rowat, A. C. ; Lee, D. ; Agresti, J. J. ; Utada, A. S. ; Chu, L. - Y. ; Kim, J. - W. ; Fernandez-Nieves, A. ; Martinez, C. J. ; et al. Designer emulsions using microfluidics. Materials Today 2008, 11, 18-27. Copy at
2008_mattoday_shah.pdf2.49 MB


We describe new developments for the controlled fabrication of monodisperse emulsions using microfluidics. We use glass capillary devices to generate single, double, and higher order emulsions with exceptional precision. These emulsions can serve as ideal templates for generating well-defined particles and functional vesicles. Polydimethylsiloxane microfluidic devices are also used to generate picoliter-scale water-in-oil emulsions at rates as high as 10 000 drops per second. These emulsions have great potential as individual microvessels in high-throughput screening applications, where each drop serves to encapsulate single cells, genes, or reactants.


Times Cited: 156

Last updated on 04/07/2014