Publications

2016
Spencer, S. J. ; Tamminen, M. V. ; Preheim, S. P. ; Guo, M. T. ; Briggs, A. W. ; Brito, I. L. ; Weitz, D. A. ; Pitkanen, L. K. ; Vigneault, F. ; Virta, M. P. J. ; et al. Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers. ISME JOURNAL 2016, 10, 427-436. 2016_isme_spencer.pdf
Wagner, O. ; Thiele, J. ; Weinhart, M. ; Mazutis, L. ; Weitz, D. A. ; Huck, W. T. S. ; Haag, R. Biocompatible fluorinated polyglycerols for droplet microfluidics as an alternative to PEG-based copolymer surfactants. Lab on a Chip 2016, 16, 65–69. 2016_labchip_wagner.pdf
Park, J. - S. ; Kim, D. ; Shin, J. H. ; Weitz, D. A. Efficient nematode swimming in a shear thinning colloidal suspension. Soft Matter 2016, -. Publisher's VersionAbstract

The swimming behavior of a nematode Caenorhabditis elegans (C. elegans) is investigated in a non-Newtonian shear thinning colloidal suspension. At the onset value ([curly or open phi] [similar] 8%), the suspension begins to exhibit shear thinning behavior, and the average swimming speed of worms jumps by approximately 12% more than that measured in a Newtonian solution exhibiting no shear dependent viscosity. In the shear thinning regime, we observe a gradual yet significant improvement in swimming efficiency with an increase in [curly or open phi] while the swimming speed remains nearly constant. We postulate that this enhanced swimming can be explained by the temporal change in the stroke form of the nematode that is uniquely observed in a shear thinning colloidal suspension: the nematode features a fast and large stroke in its head to overcome the temporally high drag imposed by the viscous medium, whose effective viscosity ([small eta]s) is shown to drop drastically, inversely proportional to the strength of its stroke. Our results suggest new insights into how nematodes efficiently maneuver through the complex fluid environment in their natural habitat.

2016_soft_matter_park.pdf
Henderson, S. J. ; Xia, J. ; Wu, H. ; Stafford, A. R. ; Leslie, B. A. ; Fredenburgh, J. C. ; Weitz, D. A. ; Weitz, J. I. ; others,. Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure. Thrombosis and haemostasis 2016, 115, 115. 2016_thrombosis_haemostasis_henderson.pdf
2015
Amstad, E. ; Spaepen, F. ; Weitz, D. A. Crystallization of undercooled liquid fenofibrate. Physical Chemistry Chemical Physics 2015, 17, 30158–30161. 2015_pccp_amstad.pdf
Rotem, A. ; Ram, O. ; Shoresh, N. ; Sperling, R. A. ; Goren, A. ; Weitz, D. A. ; Bernstein, B. E. Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state. Nature biotechnology 2015, 33, 1165–1172. 2015_natbiotech_rotem.pdf
Jensen, M. H. ; Morris, E. J. ; Weitz, D. A. Mechanics and dynamics of reconstituted cytoskeletal systems. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 2015, 1853, 3038–3042. 2015_bba_jensen.pdf
Vogel, N. ; Utech, S. ; England, G. T. ; Shirman, T. ; Phillips, K. R. ; Koay, N. ; Burgess, I. B. ; Kolle, M. ; Weitz, D. A. ; Aizenberg, J. Color from hierarchy: Diverse optical properties of micron-sized spherical colloidal assemblies. Proceedings of the National Academy of Sciences 2015, 112, 10845–10850. 2015_pnas_vogel.pdf
Hackelbusch, S. ; Rossow, T. ; Steinhilber, D. ; Weitz, D. A. ; Seiffert, S. Hybrid Microgels with Thermo-Tunable Elasticity for Controllable Cell Confinement. Advanced healthcare materials 2015, 4 1841–1848. 2015_advhealthmater_hackelbusch.pdf
Zhang, H. ; Cockrell, S. K. ; Kolawole, A. O. ; Rotem, A. ; Serohijos, A. W. R. ; Chang, C. B. ; Tao, Y. ; Mehoke, T. S. ; Han, Y. ; Lin, J. S. ; et al. Isolation and analysis of rare norovirus recombinants from co-infected mice using drop-based microfluidics. Journal of virology 2015, JVI–01137. 2015_jvi_zhang.pdf
Abbaspourrad, A. ; Zhang, H. ; Tao, Y. ; Cui, N. ; Asahara, H. ; Zhou, Y. ; Yue, D. ; Koehler, S. A. ; Ung, W. L. ; Heyman, J. ; et al. Label-free single-cell protein quantification using a drop-based mix-and-read system. Scientific reports 2015, 5. 2015_srep_abbaspourrad.pdf
Utech, S. ; Prodanovic, R. ; Mao, A. S. ; Ostafe, R. ; Mooney, D. J. ; Weitz, D. A. Microfluidic Generation of Monodisperse, Structurally Homogeneous Alginate Microgels for Cell Encapsulation and 3D Cell Culture. Advanced healthcare materials 2015, 4 1628–1633. 2015_advancedhealthcarematerials_utech.pdf
Mazutis, L. ; Vasiliauskas, R. ; Weitz, D. A. Microfluidic Production of Alginate Hydrogel Particles for Antibody Encapsulation and Release. Macromolecular Bioscience 2015, n/a–n/a. Publisher's Version 2015_macromolecularbioscience_mazutis.pdf
Chang, C. B. ; Wilking, J. N. ; Kim, S. - H. ; Shum, H. C. ; Weitz, D. A. Monodisperse Emulsion Drop Microenvironments for Bacterial Biofilm Growth. Small 2015, 11, 3954–3961. Publisher's Version 2015_small_chang.pdf
Wagner, O. ; Zieringer, M. ; Duncanson, W. J. ; Weitz, D. A. ; Haag, R. Perfluoroalkyl-Functionalized Hyperbranched Polyglycerol as Pore Forming Agents and Supramolecular Hosts in Polymer Microspheres. International journal of molecular sciences 2015, 16, 20183–20194. 2015_ijms_wagner.pdf
Tao, Y. ; Rotem, A. ; Zhang, H. ; Chang, C. B. ; Basu, A. ; Kolawole, A. O. ; Koehler, S. A. ; Ren, Y. ; Lin, J. S. ; Pipas, J. M. ; et al. Rapid, targeted and culture-free viral infectivity assay in drop-based microfluidics. Lab on a Chip 2015, 15, 3934–3940. 2015_labchip_tao.pdf
Arriaga, L. R. ; Amstad, E. ; Weitz, D. A. Scalable single-step microfluidic production of single-core double emulsions with ultra-thin shells. Lab on a Chip 2015, 15, 3335–3340. 2015_labchip_arriage.pdf
Park, J. - A. ; Kim, J. H. ; Bi, D. ; Mitchel, J. A. ; Qazvini, N. T. ; Tantisira, K. ; Park, C. Y. ; McGill, M. ; Kim, S. - H. ; Gweon, B. ; et al. Unjamming and cell shape in the asthmatic airway epithelium. Nature materials 2015, 14, 1040–1048. 2015_natmater_park_ja.pdf
Han, H. - S. ; Cantalupo, P. G. ; Rotem, A. ; Cockrell, S. K. ; Carbonnaux, M. ; Pipas, J. M. ; Weitz, D. A. Whole-Genome Sequencing of a Single Viral Species from a Highly Heterogeneous Sample. Angewandte Chemie 2015. 2015_angewchem_han.pdf
Tao, Y. ; Rotem, A. ; Zhang, H. ; Cockrell, S. K. ; Koehler, S. A. ; Chang, C. B. ; Ung, L. W. ; Cantalupo, P. G. ; Ren, Y. ; Lin, J. S. ; et al. Artifact-Free Quantification and Sequencing of Rare Recombinant Viruses by Using Drop-Based Microfluidics. ChemBioChem 2015, n/a–n/a. Publisher's Version 2015_chembiochem_tao.pdf

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