Citation:
Martino, C. ; Kim, S. - H. ; Horsfall, L. ; Abbaspourrad, A. ; Rosser, S. J. ; Cooper, J. ; Weitz, D. A. Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures. Angewandte Chemie-International Edition 2012, 51, 6416-6420. Copy at http://www.tinyurl.com/y2apll7j
 | martino2012.pdf | 1.22 MB |
Abstract:
Bringing droplets to life: A cytoskeletal protein (red dots, see scheme) is expressed in artificial cells composed of biocompatible polymersomes, which encapsulate expression machinery and amino acid building blocks. Release of the expressed proteins can be triggered by a negative osmotic shock.